Myles of Science: December 2014

I hope you all enjoy a relaxing holiday break with family and friends

LiD ceremony - determination of LiD questions announced

Research LiD Question

Science 10

Quiz 8.1
finish lab 8-1F
soup can demo and analysis
read pgs. 362-363 & fill in foldable

Biology 12 - same as yesterday

Interesting Bioethics Article about chimeric cells

http://www.scientificamerican.com/article/scientists-discover-childrens-cells-living-in-mothers-brain/?WT.mc_id=SA_Facebook

Wednesday, December 17th

Science 10 - QUIZ 8.1 & Same lesson as yesterday

Biology 12 - Research ethical question

Tuesday, December 16th

Science 8

1. Hand in LiD question
2. Hand in good copy of immune system map
3. Quiz 3.1
4. Read pgs. 110-114 & fill in chart
5. CYU questions #2,3,7,10 on page 117

Science 10

Review Activity 8-1F

https://www.youtube.com/watch?v=UoUzp6Wo638

https://www.youtube.com/watch?v=x2ve5yucNPQ

Click to Run

Complete Lab 8-1F
Review questions pg.361

Biology 12 - Same as Monday, December 15th

Monday, December 15th

Science 10 - Same as Friday, December 12th

Biology 12

1. Protein Synthesis & Mutations Quiz
2. Pick up practice workbook
3. Start Bioethics Project & choose ethical question

Biology 12 - Bioethics Project Links

Referencing Instructions:

To prepare for the Bioethics Project choose at least two of the articles to read. You are welcome to search and find additional articles (possible sources: UBC, SFU, CBC, BBC, Discover, Scientific American).

Reference the articles you read and found useful for the Bioethics Project (include the article title and link).

Please provide the titles & links at the bottom of the page (or on an additional page) when you submit your answer to question #6. This submission should be typed.

Article links:

Genetically modified potatoes

GMOs

Gene Therapy

Gene doping

Genetic disorder link

Genetic disorder - CSID

Genetic disorder - Cystic fibrosis

Genetic Disorder - Scizophrenia

Genetic Disorder - Autism

Genetic Disorder - Down Syndrome

Genetic Disorder - Marfan's Syndrome

Genetic Disorder - Huntingtons Disease

Genetic Disorder - Heart disease

Genetic Engineering

Friday, December 12th

Science 8

Review RC

Finish mapping activity & hand it in

Complete review questions on pg. 109

RESET portfolios for Term 2

Homework - select questions for LiD project

Science 10

Review RC on pg. 351

Read pgs. 353-354

Complete activity 8-1D

Start formal lab 8-1F

Biology 12

Same as December 11th

Thursday, December 11th

Science 10 - Same as December 10th

Biology 12

Hand in Vitamin C assignment

Finish GATTACA movie & journal page

Reminder - Protein synthesis/Mutation quiz next class

Learning Outcomes for quiz:

Identify roles of DNA, mRNA, tRNA and ribosomes in transciption and translation
Determine a sequence of amino acids from DNA using a mRNA codon table
Use examples to explain how mutations in DNA change the sequence of amino acids and as a result may lead to genetic disorders
Define and give examples of mutagens

DNA Replication Update:

Here is some more information on DNA Replication & a 'interesting' rap that clearly explains the whole process...

Rap Video: https://www.youtube.com/watch?v=1L8Xb6j7A4w

DNA Replication is Semi-Conservative

DNA replication of one helix of DNA results in two identical helices. If the original DNA helix is called the "parental" DNA, the two resulting helices can be called "daughter" helices. Each of these two daughter helices is a nearly exact copy of the parental helix (it is not 100% the same due to mutations). DNA creates "daughters" by using the parental strands of DNA as a template or guide. Each newly synthesized strand of DNA (daughter strand) is made by the addition of a nucleotide that is complementary to the parent strand of DNA. In this way, DNA replication is semi-conservative, meaning that one parent strand is always passed on to the daughter helix of DNA.

The first step in DNA replication is the separation of the two DNA strands that make up the helix that is to be copied. DNA Helicase untwists the helix at locations called replication origins. The replication origin forms a Y shape, and is called a replication fork. The replication fork moves down the DNA strand, usually from an internal location to the strand's end. The result is that every replication fork has a twin replication fork, moving in the opposite direction from that same internal location to the strand's opposite end.

When the two parent strands of DNA are separated to begin replication, one strand is oriented in the 5' to 3' direction while the other strand is oriented in the 3' to 5' direction. DNA replication, however, is inflexible: the enzyme that carries out the replication, DNA polymerase, only functions in the 5' to 3' direction. This characteristic of DNA polymerase means that the daughter strands synthesize through different methods, one adding nucleotides one by one in the direction of the replication fork, the other able to add nucleotides only in chunks. The first strand, which replicates nucleotides one by one is called the leading strand; the other strand, which replicates in chunks, is called the lagging strand.

The Leading Strand

Since DNA replication moves along the parent strand in the 5' to 3' direction, replication can occur very easily on the leading strand. As seen in , the nucleotides are added in the 5' to 3' direction. Triggered by RNA primase, which adds the first nucleotide to the nascent chain, the DNA polymerase simply sits near the replication fork, moving as the fork does, adding nucleotides one after the other, preserving the proper anti-parallel orientation.

The Lagging Strand

The lagging strand replicates in small segments, called Okazaki fragments. These fragments are stretches of 100 to 200 nucleotides in humans that are synthesized in the 5' to 3' direction away from the replication fork. Yet while each individual segment is replicated away from the replication fork, each subsequent Okazaki fragment is replicated more closely to the receding replication fork than the fragment before. The lagging strand must wait for a patch of the parent helix to open up a short distance in front of the newly synthesized strand before it can begin its synthesis back to the end of the daughter strand. This "lag" time does not occur in the leading strand because it synthesizes the new strand by following right behind as the helix unwinds at the replication fork.

These fragments are then stitched together by DNA ligase, creating a continuous strand.

Wednesday, December 10

Science 8

Review Activity 3-1

Watch Immune System Video

Read pgs. 102-105 & complete RC on pg.106

Start Immune System mapping activity

Science 10

Physics 8.1

Review RC pg. 347 & pgs. 344-347

Read pgs 348-351 --> add to foldable notes

Complete Activity 8-1B, 8-1C in notebooks

Homework - RC pg. 351 #1-3

Biology 12

Same as December 9th

Tuesday, December 9th

Science 10

(Same as yesterday - Monday, December 8th)

Biology 12

The Vitamin C Activity is due today - please hand it in.

We are starting our Bioethics Project today by watching GATTACA.

Please use the handout to create the journal page below...

Monday, December 8

Congratulations Mr.Wenzel for completing his teaching practicum!

Mrs. Myles returns to Science 8 & 10 today

Science 8

How does the immune system protect the human body?

Complete human body project reflection

Read pgs.98 & 100

Create journal page - 4 ways to...

Complete activity 3-1

Science 10

Physics Chapter 8.1

Read pg.340-341

Complete activity on pg.341

Create foldable and paste into workbooks pg.343

Read pg. 344-347 & fill in part of the foldable

Homework - reading check pg.347

Biology 12

Mutation Videos
https://www.khanacademy.org/test-prep/mcat/biomolecules/genetic-mutations/v/an-introduction-to-genetic-mutations

Mutation Reading

Vitamin C Mutations Lab - Due next class

December 5

Biology 12